CircularFLO will convert any existing, or new, InDesign or PDF documents you may have. There is no limitation or restriction on the physical page size, the page proportions or the type and colour space of graphics used. The only restriction of the fixed layout standard is that all pages in one book are the same.
Users sometimes assume they should prepare pages or images at a certain screen proportion, resolution or pixel size or should modify the graphics used. This is unnecessary as all this work is done automatically as part of the conversion process.
If your do wish to alter the graphic file size and quality you should not amend your InDesign file or graphics but instead see the JPEG compression options in the Preferences Panel.